Serum marker offer alternative for colorectal cancer detection

27. 01. 2011 |

A combination of six serum markers to detect colorectal cancer (CRC) was found to be comparable to the performance of fecal immunochemical testing, finds a study in Clinical Cancer Research [1].

Serum marker offer alternative for colorectal cancer detection

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The early detection of CRC significantly improves the prognosis of patients and is a key factor for reducing mortality. The current practice of CRC screening is based around fecal occult blood testing (FOBT) or fecal immunochemical testing (FIT), with patients who test positive referred to a specialist for colonoscopy. But the difficulty of such approaches is that patient compliance with stool based assays tends to be low.

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  1. Wild N, Andres H, et al. A combination of serum markers for the early detection of colorectal cancer. Clinical Cancer Research 2011. doi: 10.1158/1078-0432.CCR-10-0119

Keywords: serum markers, faecal immunochemical test (FIT), immunological faecal occult blood test (iFOBT), colorectal cancer